Lot of people carry the 642 in a coat pocket. If I were to do that there would be no loose change or anything else in there but the gun and yes it could be shot from inside the coat pocket. That would not be my first choice but if push comes to shove it will work. That might especially work well if you were using the Hornady personal defense ammo.
By faith Noah,being warned of God of things not seen as yet, moved with fear,prepared an ark to the saving of his house;by the which he condemned the world,and became heir of the righteousness which is by faith Heb.11:7