10mm ammo is more expensive, but I order most of my ammo online so finding it isn't as big a problem. The price is an issue.
I do have a few S&W revolvers. A 1909 .38 special, 22/32 kit gun, 18-4, and a 442 which I carry. That is one reason why I am considering the .357 so I can save money and use .38 special as well as .357 ammo.
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I shot my cousins Colt Double Eagle in 10mm .... other than the slide speed being incredibly fast I found the recoil to be tolerable. I have a Ruger Redhawk in .480 and I found that to be heavier in the recoil department. Each person has their own level of tolerance to recoil though. Maybe you can rent a 10mm at a local range and see if it bothers you.
NRA Life Member, NH CC, Gun Owners of America, Citizens Committee for the Right to Keep and Bear Arms, Second Amendment Foundation
"Remember, incoming fire has the Right of Way"
Most of the gun shops don't have any 10mm in stock, and the ones with ranges I haven't been able to find a 10mm to rent. Unfortunately it doesn't seem to be as popular as the other calibers I mentioned. I go back and forth between the 10mm and .45 as there are good reasons to go with each caliber. I have better reasons to go with the .357, but most of the S&W I see are more expensive than a new semi.
I was looking at the EAA Witness Match in 10mm, but now thinking about it in .45 as well as looking at the .357s. I appear to be back at square one.
I use the .45s but would not mind owning a S&W 1006 to match the 645.