ALL good points. I CC a Taurus Mod 64B loaded with 357 Mags. This weapon comes with Factory Pachmayer Grips. At times I will load with .38 +P's if I'm CC'ing my 45 so my wife can handle more comfortably at home. Priced at about $ 500.00. S&W's will be about a third more but better resale, COLT are double the price.
Your choice of weapons depends on a lot of factors. Other then the basics, your size/build/hand size. Your ability to shoot accurately with the least amount of discomfort should be the deciding factor. 38+P's will give you good knock down and wad cutters are cheap on the range. I personally keep semi jacketed magnums if I CC this weapon. Pricey but haven't had to expend one yet, thank God. ALWAYS load for the worse and practice with those loads as well.
"The smallest minority on earth is the individual. Those who deny individual rights cannot claim to be defenders of minorities." --author and philosopher Ayn Rand (1905-1982)